Tempo Therapeutics is a therapeutic device company creating innovative material science solutions for tissue engineering in regenerative medicine with our patent-protected MAP synthetic materials to build new functional tissue in patients and improve outcomes 10-fold over current available products.

Meet Tempo Therapeutics

Tempo Therapeutics is a late development stage therapeutic device company creating innovative material science solutions for tissue engineering in regenerative medicine, beginning with complex wounds; a multi-billion dollar market opportunity, and extending into cardiac, neural, and orthopedic indications with huge unmet needs. Our technology can build new functional tissue in these indications and transform patient care. Current tissue engineering technologies cannot meet patient needs, because these implants are rejected by the patient's immune system, and are unable to build new tissue and restore organ function. Tempo meets this critical unmet need with our patent-protected MAP biomaterial technology. MAP enables fully-synthetic injectable implants that, through critical immune privilege, build NEW tissue within patients, in real time - without the need for delivery of any biologics or cells. MAP empowers patient biology to build tissue within our synthetic materials - recognized by immune cells as 'self' and avoiding the foreign body response that limits the efficacy of all other current and emerging technologies in tissue engineering. Since beginning operations in mid 2016, Tempo has achieved the following important milestones- significantly de-risking the company and providing a clear path to market: • Winning over $1.7M in non-diluting grant funding from the NIH • Submitting our first product, TT101, to FDA for approval as a medical device • Receiving awarded patents covering composition, manufacturing, and methods of use • Building a scaled and cGMP-ready manufacturing process • Treating >20 real-world cases of complex wounds in veterinary medicine with 100% success • Completing independent animal study validations of TT101 with potential corporate partners • Innovative R&D efforts to expand our patent portfolio and pipeline indications beyond complex wounds to medical aesthetics, orthopedics, cardiac, and vaccine technology. Our initial success with TT101 de-risks regulatory activity, a partnership development model, and will enable a fast path to revenue to increase company value. Tempo's unique MAP technology provides opportunity in many therapeutic areas including tissue atrophy and medical aesthetics - multi-billion dollar markets in which Tempo has already developed candidates. Further, our technology reaches even broader into high growth therapeutic areas including neural repair, cardiac repair, cell therapy, vaccine technology, and drug delivery.

Why is your company the best option to solve the problem you're solving?

Our MAP technology makes Tempo the best option to solve the problem of tissue regeneration. MAP has unique properties of immune privilege, which enables Tempo to create injectable implants that are accepted and integrated into the body, rather than rejected. This core capability provides unique competitive advantage and the ability to achieve therapeutic outcomes that no other material technology can. Tempo is the sole provider of MAP-enabled implants, and will change the way that tissue engineering affects medical treatment across many areas of medicine.

What nuggets of info make you interesting? Why do people care about what you're doing?

Our company builds on a long standing tradition of tissue engineering innovation in San Diego. One of the first companies to develop tissue engineering technology - Advanced Tissue Sciences, was born and built in San Diego. Even the term "Tissue Engineering" was coined by a UCSD professor in the mid 1980's. We are taking Tissue Engineering to the next level with our core MAP technology, and can work with the San Diego companies operating in 3D Printing, stem cell technology, and pharmaceuticals to accelerate product development.

What else do you want us to know?

We are a spin out from UCLA, formed by scientists, engineers, and physicians - all dedicated to the core task of seeing MAP-enabled products reach patients and change their lives for the better. We have been able to build a strong team here in San Diego, - bringing in expertise in management and product development from San Diego's strong talent pool. We are centralized around a core technology that we all believe in, and are exploring where this technology can add value in all verticals of medicine.

BEHIND THE COMPANY

Founder/CEO: Westbrook Weaver

What is your company's secret sauce?

A combination of technology capability (immune privilege) and patent protection around the MAP technology.

What inspired you (CEO/Founder) to start/run this company?

I was a scientist in academia when we invented the core technology that Tempo is now based upon. I decided to leave academia and start Tempo because I wanted to see something real come from our work - something that could actually positively affect a patient's life. That is my mission, and remains my central ethos to this day.

What sets your company culture apart?

We all come from a technical background, even our management team (who also have many years of life science management under our belts). This helps us focus on our core values of scientific rigor to support robust product development, and centralize around a core technology that can have many product opportunities through medicine.

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