Drumroll… Announcing the 2020 Cool Companies!

May 28, 2020

San Diego’s fastest growing and most exciting tech & lifesci companies.

Thank you 2020 Cool Companies Sponsors

Every year we gather hundreds of tech and lifesci startup applications, selecting around 30 to introduce to over 100 VCs from across the country. Considering the current environment, and in lieu of physical constraints — we are excited to announce a much larger pool of companies this year, with over half life sciences.

Announcing the 2020 Cool Companies - Greetings from Mike Krenn, CEO
Mike Krenn, CEO of Connect, welcome the 2020 Cool Companies.

1859

1859 is creating a pico-scale HTS platform (pico-HTS) that enables us to test millions of potential medicines in a single day. Our technology also allows us to rapidly explore chemical space and construct novel chemical diversity “on-demand”. This allows us to discover more medicines and get them to the clinic faster. At scale our technology […]

Connect San Diego California 2021 Life Science Innovation Startup Business Company Abterra Bio 01

Abterra Bio

Abterra Bio uses machine learning to mine the human immune system to discover novel antibody therapeutics. Patients mount lasting antibody responses to infectious diseases and cancer. Our platform uses next-generation sequencing and mass spectrometry data to comprehensively map this antibody response, rapidly identifying better therapeutic antibodies. We’ve built an interdisciplinary team of data scientists and […]

Aequor

Aequor is a woman-owned small business with a large portfolio of proprietary chemical compounds discovered in the ocean that are non-toxic, “green,” and natural antimicrobials.

Arborea

Arborea has developed the most efficient ingredients & proteins production platform that solves the crucial issues of existing photosynthetic culture platforms.

Believe Health

Believe Health builds virtual care programs that specialty doctors can provide to their patients.

Benchmark Labs

Benchmark Labs combines grid level weather data with site-based IoT sensors, and uses their proprietary AI software to provide precise asset-located weather forecasting to optimize renewable energy generation & water allocation, reduce spatial basis risk and maximize financial benefits.

Biocanic

Biocanic is a HIPAA compliant Software as a Service (SaaS) integrative health and medicine platform (also known as “functional medicine”) designed to simplify personalized health plans into an easy-to-understand language for both practitioners and their clients. Biocanic digitizes all aspects of health improvement plans to build a machine learning engine. Through the Biocanic platform, we […]

Carlsmed

Carlsmed is the first and only company to use patient outcome data to create personalized surgical plans and personalized implants for spine surgery. Carlsmed provides personalized solutions to decrease surgery time, decrease healthcare cost, and improve patient outcomes.

Cella Medical

Cella Medical, EvoNexus portfolio company, developed a small device CELLA for personal use to reduce the number of doctor visits and hospitalizations for chronic kidney and heart failure patients. They can for the first time manage their disease by measuring fluid buildup in the comfort and privacy of their homes.

Ceresti Health

Ceresti Health is a digital health company that specializes in the early detection and prevention of costly acute events such as emergency department visits and hospitalizations.

Chilldyne

Chilldyne is a technology enables water to be used for direct-to-chip cooling of CPUs in high performance computers and servers.

Circumvent

Circumvent has created a proprietary platform that identifies underlying biology that drives neurodegenerative disease in both pediatric and aging dementia patients.

Commsafe AI

CommSafe AI is a SaaS company that specializes in conflict and violence prevention. The CommSafe AI technology flags and labels employee communication containing triggers of toxic communication. Once a communication is triggered, the technology automatically sends an alert to HR, making them aware of the otherwise hidden liability, and provides them with next step recommendations. […]

Connect San Diego California 2021 LifeSci BioTech Startup Business Company Concert Health 01

Concert Health

Concert Health helps independent physician practices deliver integrated behavioral health services to their patients. 2019 – Raised $2.2M seed round

Cybele Microbiome

Cybele Microbiome

Cybele Microbiome has a platform to harness the powerful natural factory that exists on every human: the microbiome. This is a new paradigm for producing bio-based compounds “in place” that are personalized, natural, long-lasting, vegan, sustainable, environmentally friendly, and cheaper and faster to develop than traditional industrial methods.

Daasity

A Data-as-a-Service company that provides a proprietary end to end platform for small and medium sized direct-to-consumer companies to truly harness their data for better business decisions.

Educational Vision Technologies

EVT uses artificial intelligence to autonomously generate online courses for universities and training programs for corporations to enable efficient learning and a substantial cost reduction for creating digital learning.

Esguard.io

Esguard.io Corporation is all about making connecting to the Internet faster, safer, and better.

FormAlloy

Formalloy is a 3D metal printing company which utilizes Laser Metal Deposition (LMD) technology that provides an innovative, cost-effective solution for 3D metal part production, repair and coatings to diverse industries.

formsense

formsense technology powers the next generation of compression apparel and sports training equipment that provides the first-ever volumetric assessment of athletic form in real-time to elevate performance and prevent injuries

Galley Solutions

Galley helps restaurants, caterers, and other types of food businesses collect and understand the food data behind their operations.

GameTree

GameTree social network that recommends friends, games, and gaming sessions.

Global BioTherapeutics USA

Global BioTherapeutics has developed a novel vector delivery method to the liver that has yielded unprecedented results, Compartmentalized Liver Transduction (CLT).

2022 Cool Co Logos

GoShare

We use technology to improve last-mile delivery and moving experiences for our customers. Our mission is to organize the world’s trucks to make them more accessible and useful. Our vision is to create the largest network of trucks in the world. More than 90,000 customers and 12,000 Delivery Professionals trust GoShare to deliver. 2019, 2020, […]

Gryphon

Gryphon is a cloud managed network protection platform powered by adaptive machine learning targeting the connected home and small businesses with a re-occurring business model. Gryphon combines speed, parental control, and intelligent cyber protection in a simple plug and play mesh router.

Hallo

Hallo is a live streaming community for language learning.

Hemaflo Therapeutics

HemaFlo Therapeutics

HemaFlo is developing a novel treatment for acute kidney injury (AKI).

HUMBL

HUMBL LLC is a financial services company that travels with you beyond legacy systems, traditional bank branches, and physical borders. right from your mobile phone.

iAssay

iAssay developed an open platform for wireless Point of Care (POCT) diagnostics.

Innovega

Innovega has developed a new generation of patented Contact Lenses that enable wearers to experience rich digital media experiences from stylish, lightweight Glasses.

KAST

Your live hangout where you share your experiences. Watch movies with 100+ friends, play and share games, watch sports, hangout, and more!

La Jolla NanoMedical

La Jolla NanoMedical

La Jolla NanoMedical is a platform product for non surgical treatment of skin cancer and certain other cancers.

Lipidio Pharmaceuticals

Lipidio is a development stage biopharma focused on diseases associated with excess body fat.

Lotus Trolley Bag

Lotus Trolley Bag is a reusable system & sustainable solution to plastic. In the past 2 quarters, we have grown from 600 to 10,000 retail stores in the U.S. and Canada. Experienced team, scalable model, dedicated production facility & an omnichannel sales approach. Revenue for 2019 is at $2.7M & tracking for $10M in revenue […]

MatriSys Bioscience

MatriSys Bioscience focuses on the $142 Billion worldwide dermatology and skin care market by developing microbiome-derived therapies for the top dermatology and skin care conditions – Acne, Atopic Dermatitis (AD), Rosacea, Psoriasis, and Skin Infections which have a huge impact on 230 million patients’ quality of life.

MediPrint Ophthalmics

MediPrint Ophthalmics

MediPrint Ophthalmics (FKA Leo Lens Pharma) is an emerging San Diego-based clinical stage eye care pharmaceutical company focused on enhancing vision for life by developing and commercializing a proprietary ocular drug delivery portfolio. There are over 40 million soft contact lens wearers in the United States alone and most of them will develop some eye […]

MemComputing

MemComputing delivers quantum computing performance to any computer with our software-based MemCPU(tm) Coprocessors. Developed at UC San Diego by two PhD Physicists.

Micronoma

We are a team of veterans of Microbiome and Life Sciences / Biotech. We are really cool bunch of people who know how to work hard and still have fun!

Neuralace Medical

NeuraLace Medical

NeuraLace Medical is a startup medical device company founded in San Diego whose bold mission is to disrupt the chronic pain epidemic.

NVISNx

NVISNx is an innovative cyber solutions platform developer for Fortune 500 thru emerging companies.

Origami Therapeutics

Origami Therapeutics

Origami Therapeutics is taking a precision medicine approach to discover disease-modifying treatments for neurodegeneration caused by toxic protein misfolding.

OrPro Therapeutics

OrPro Therapeutics

OrPro Therapeutics, Inc. (San Diego, CA) is developing a therapeutic platform based on thioredoxin, a human protein disulfide-reducing enzyme with unique mucus-normalizing, anti-inflammatory and anti-infective properties.

PhotoCulture

PhotoCulture is a curated photo contest app, designed especially for Instagram influencers and their fans. The app provides an innovative way for influencers to generate substantial income, engage with their audience in a fresh way, and provide money for the charity of their choice. PhotoCulture has phenomenal scalability; a few dozen influencer clients will result in millions of paying customers.

Realwave

Realwave is a real-time exception monitoring and automation service that analyzes all video and associated data, alerts users to critical and interesting events, and enables users to improve their operating performance.

Rejuvenate Bio

Rejuvenate Bio, a spinout from George Church, couples gene therapy, which makes precise biological changes with limited unintended effects, with longevity-based genes, which have the ability to affect aging and come with robust safety profiles.

Robolink

Robolink was established in San Diego, California to encourage students to engage with STEM. We make fun and approachable robotics kits that bring computer science to life and teach real industry competency.

Targetable

Targetable has virtualized all of the operations of a digital ad agency into one simple, easy-to-use, SaaS platform, designed exclusively for retail clients. By using a unique blend of data together with an advanced AI algorithm, Targetable automatically generates digital marketing campaigns that are faster, cost exponentially less, and perform better than a traditional agency […]

Tempo Therapeutics

Tempo Therapeutics is a therapeutic device company creating innovative material science solutions for tissue engineering in regenerative medicine with our patent-protected MAP synthetic materials to build new functional tissue in patients and improve outcomes 10-fold over current available products.

The Atlas

The Atlas is an online community of city officials modernizing the $1.6T local government market.

The Crafter’s Box

The Crafter’s Box is an e-commerce marketplace for arts & crafts digital education and materials offering a 360 degree alternative to the traditional brick-and-mortar retail experience of shopping at, say, a Hobby Lobby or Michaels.

Tiled

Tiled is a microapp platform. A microapp is an informational interactive content experience that is built without code. Tiled microapps enable sales, marketing and HR teams to have more effective conversations and communication.

TradeSun

TradeSun is an Edison Award winning Artificial Intelligence (AI) and patent pending trade finance blockchain-enabled platform that automates the adjudication of trade finance contracts while simultaneously intercepting regulatory and fraudulent infractions.

Trials.ai

The Trials.ai Smart Protocol solution leverages frontier technology to intelligently guide research teams through the process of designing their clinical trials, saving Pharma, Biotech & Device companies time and money.

UCAP Power

UCAP Power, Inc. brings commercially available Ultracapacitor technology into the mainstream.

Universal Devices

We truly believe we are nothing without our customers and our developers. We truly believe in, and practice, doing the right thing even if it's harder. And, most importantly, we are still geeks who love imagining things and bringing them into life.

Vektor Medical

Vektor Medical is a medical technology company focused on non-invasive arrhythmia mapping for improving cardiac care and patient quality of life. Vektor’s patented vMap technology analyzes ECG signals in proprietary algorithms to provide multi-chamber 2D cardiac information and interactive 3D color maps for analysis by a physician. vMap can be used in the clinical environment, such as the EP lab and the patient’s bedside. vMap is non-invasive, rapid, and designed for the clinical workflow.

Veriskin

Veriskin is a medical device company dedicated to facilitating and improving the accuracy of skin cancer screening.

Vivid Genomics

Vivid Genomics is a precision medicine company dedicated to improving the success of drug development in neurodegenerative disease.

Water Pigeon

Water Pigeon captures photos of a meter face and runs optical meter reading software to create a numerical reading for the utility.

XILO

XILO

XILO helps insurance agencies compete against rising digital competition with an easy to use, fully customizable software platform they can use to engage with their customers, provide instant insurance quotes and automate sales workflows. As part of the next generation of agency technology, XILO is aiming to disrupt old muti-billion dollar incumbents who control the […]

yuFlu

yuFlu is the first DTC sequencing as a service screen for COVID-19 & other respiratory infections that uses FDA-cleared collection devices.

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